Saturday, March 12, 2011

How does a person inherit this genetic disorder? Dominat or Recessive? Genetic or Chrmosomal?

Trisomy 13 is a chromosomal disorder, it is caused by the presence of an extra copy of chromosome 13 in each cell of a persons body which is the result of a random non-disjunction event in egg or sperm; usually there are 2 copies.  Non-disjunction- separation of chromosomes fail in cell division, resulting in a sperm or egg cell having an extra (47) or missing (45) chromosome. It can also be inherited by a parent in chromosomal translocation, but it is very rare. An unaffected person can carry a rearrangement of genetic material between chromosome 13 and another chromosome. There are no signs of Trisomy 13 but have an increased risk of having children with it. 

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